Multiphoton Microscopy Multiphoton - Leica TCS SP8 MP (Botinst) The Leica multiphoton microscope allows imaging of thick samples using two- and three-photon fluorescence excitation. An additional confocal detection path together with the possibility of supercontinuum visible excitation allows very flexible experiments. Multiphoton - Leica SP8 MP DIVE FALCON (Irchel) The Leica multiphoton microscope allows imaging of thick samples using two- and three-photon fluorescence excitation together with fully spectral detection. A confocal detection path together with supercontinuum visible excitation allows for very flexible experiments. FLIM capable detectors and acquisition hardware allow FLIM measurements with single as well as multiphoton excitation. Multiphoton - Custom Built Microscope (Irchel) The custom-built multiphoton microscope allows highly flexible in-vivo imaging with deep tissue penetration and very good optical resolution. A state of the art laser system allows the excitation of fluorophores all over the visible spectrum.