The Center for Microscopy and Image Analysis (ZMB) is a leading technology platform for advanced light and electron microscopy, serving academic and industry researchers across Zurich and beyond. With over 40 years of experience, we provide cutting-edge imaging technologies, expert consulting, and comprehensive training to help scientists generate high-quality, reproducible data. Researchers are welcome to use our systems independently, or work with us through hands-on support and collaborative imaging projects—where our specialists can design and carry out the experiments for you. Our mission is to empower the scientific community with the tools and expertise needed to advance discovery.
The Center for Microscopy and Image Analysis is a technology platform specialized in high end light and electron microscopy, supporting the research community at the University of Zurich. Our mission is to give our scientists the tools and technical expertise they need to generate reliable and reproducible scientific data using state-of-the-art microscopy. Scientists from other academic organisations and industry are also welcome to use all resources. We have over 40 years of experience in educating, training, and assisting researchers using the latest cutting edge imaging techniques.
The Center for Microscopy and Image Analysis is a technology platform specialized in high end light and electron microscopy, supporting the research community at the University of Zurich. Our mission is to give our scientists the tools and technical expertise they need to generate reliable and reproducible scientific data using state-of-the-art microscopy. Scientists from other academic organisations and industry are also welcome to use all resources. We have over 40 years of experience in educating, training, and assisting researchers using the latest cutting edge imaging techniques.
The Center for Microscopy and Image Analysis is a technology platform specialized in high end light and electron microscopy, supporting the research community at the University of Zurich. Our mission is to give our scientists the tools and technical expertise they need to generate reliable and reproducible scientific data using state-of-the-art microscopy. Scientists from other academic organisations and industry are also welcome to use all resources. We have over 40 years of experience in educating, training, and assisting researchers using the latest cutting edge imaging techniques.
The Center for Microscopy and Image Analysis is a technology platform specialized in high end light and electron microscopy, supporting the research community at the University of Zurich. Our mission is to give our scientists the tools and technical expertise they need to generate reliable and reproducible scientific data using state-of-the-art microscopy. Scientists from other academic organisations and industry are also welcome to use all resources. We have over 40 years of experience in educating, training, and assisting researchers using the latest cutting edge imaging techniques.
• General inquiries • Inquiries about service feed and billing issues • Issues with access cards • New access card request (for externals) • Assistance for registration process
We provide technical and scientific support or consultation for projects involving microscopy and sample preparation. We will help you select the most appropriate instrument for your project. If necessary, sample preparation and imaging can also be requested as a service.
All instruments can be used independently by you (after the training is completed), You can reserve and use instruments 24 x 7. The ZMB staff is available to support you from 8:00 - 17:00 (Mo - Fr).
Confocal microscopy provides optical sectioning by using a laser to illuminate a sample and a pinhole to block out-of-focus light, creating detailed 3D reconstructions of cells and tissues. It offers high contrast and clarity, essential for studying complex biological processes.
Wide-field microscopy uses broad illumination to capture images of entire samples quickly and easily, ideal for observing live cells and large sample areas. It provides a comprehensive view, making it a fundamental tool for general observation and initial assessments.
Super-resolution microscopy includes techniques like pixel reasignment, Expansion microscopy, SIM, STED, and dSTORM, which surpass the diffraction limit of light, achieving high-resolution molecular imaging. These methods reveal fine details at the nanometer scale, crucial for understanding cellular mechanisms.
Light-sheet microscopy uses thin sheets of light for fast, high-contrast 3D imaging with minimal photodamage. It is beneficial for imaging large, live specimens, allowing observation of dynamic biological processes in real-time.
Multiphoton microscopy uses low-energy photons for deep tissue imaging with reduced photodamage and photobleaching. It is valuable for high-resolution imaging of thick, living tissues, and observing dynamic biological processes in real-time.
Cryo-electron microscopy (cryo-EM) rapidly freezes samples to preserve their native state, allowing near-atomic resolution imaging of biological macromolecules, providing detailed insights into the structure and function of proteins, viruses, and cellular components.
Electron microscopy (EM) uses electron beams for high-resolution imaging. TEM reveals internal structures at atomic levels, SEM provides 3D surface images, and EDX analyzes elemental composition, essential for identifying materials and studying their properties.
Sample preparation for light and electron microscopy involves tools like pipetting robot, e-beam and sputter coaters, glow discharger, ultramicrotomes, cryostat, high-pressure freezer and grid plunger.
Image analysis in microscopy processes and interprets images to extract data, enhance contrast, and visualize 3D structures. Advanced software and algorithms quantify features, identify patterns, and analyze spatial relationships, providing insights into specimen morphology and function.
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